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Medical Update

September 14, 2014


Genetically Modified Immune Cells Attack Leukemia in Adults and Children   

Three and a half years after beginning a clinical trial, supported by the National Institutes of Health, which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the Perelman School of Medicine at the University of Pennsylvania and the Children's Hospital of Philadelphia announced the latest results of studies involving both adults and children with advanced blood cancers that have failed to respond to standard therapies. The findings from the first 59 patients who received this investigational, personalized cellular therapy, known as CTL019, were presented on Saturday, December 7, 2013 during the American Society of Hematology's Annual Meeting and Exposition in New Orleans.


Genetic Re-Programming of Stem Cells to Fight Cancer 



African American Men and Oral Cancer Again

African American men are one of the groups at highest risk for oral cancer - but many don't know it. Watch this video to learn more about oral cancer and the importance of detecting the disease early when it can be treated more successfully. Brought to you by the National Institute of Dental and Craniofacial Research (NIDCR). For the National Institute of Dental and Craniofacial Research's Privacy Policy visit:  ‪


African Americans and Oral Cancer 



Key Enzyme Gene Variations Linked To Prostate Cancer  

Recently, researchers at the National Institutes of Health reported that variations in a gene for an enzyme involved in cell energy metabolism appear to increase the risk for prostate cancer. The genetic variations all impair the enzyme phosphodiesterase 11A (PDE11A), which helps regulate a cell's responses to hormones and other signals. Previous studies by this group have linked genetic variations that inactivate PDE11A with increased susceptibility to testicular cancer and adrenal tumors. In a new Web video, the study's senior author, Constantine Stratakis, M.D., D.Sc., acting director of the Intramural Research program at the NICHD, discusses the study's findings


Key Enzyme Gene Variations and Prostate Cancer 



Cervical Cancer 

Definition of cervical cancer: Cancer that forms in tissues of the cervix (the organ connecting the uterus and vagina). It is usually a slow-growing cancer that may not have symptoms but can be found with regular Pap tests (a procedure in which cells are scraped from the cervix and looked at under a microscope). Cervical cancer is almost always caused by human papillomavirus (HPV) infection (National Cancer Institute, 2014)


Cervical Cancer 



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